New research on how excess parathyroid hormone affects immune cells suggests that doctors could repurpose existing drugs to treat hyperparathyroidism without surgery.
Endocrinology, Metabolism and Lipids Division Director, Roberto Pacifici, MD, teamed up with doctors from the University of Turin in Italy, combining observations of human patients with an overactive parathyroid with experiments on mice.
Calcium channel blockers, now used to treat high blood pressure, and antibodies that block the inflammatory molecule IL-17A (under development for the skin disease psoriasis) are the potential drug treatment options.
The results of this research were recently published Cell Metabolism (abstract).
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