Researcher Spotlight: Jessica Pierce

What is your professional background?
I earned a Bachelor of Science in Biopsychology from Oglethorpe University. My graduate studies focused on investigating the endocrine mechanisms regulating bone loss and marrow fat accumulation in models of osteoporosis. Through this work, I earned a Doctor of Philosophy in Cellular Biology and Anatomy from Augusta University.

In what division do you work, and who is your mentor?
I am a postdoctoral fellow in the Division of Endocrinology, Metabolism, and Lipids. My mentor, Dr. Daniel Perrien, has expertise in musculoskeletal biology and bone biomechanics.

Briefly describe your research. Why is it important?
Our research focuses on the mechanisms underlying the rare bone disease Fibrodysplasia Ossificans Progressiva, or FOP. I am investigating the role of the gut microbiome in (1) the inflammatory immune response to muscle injury and (2) endochondral heterotopic ossification in our models of FOP. We are particularly interested in how changes in gut microbial diversity influence innate immune cell priming and monocyte/macrophage recruitment to FOP flares. Our goal is to identify mechanistic targets that lead to the development of effective therapies for FOP and models of traumatic heterotopic bone formation.

What do you like most about Emory?
I like that there are so many layers to the culture at Emory. There is always something new to discover.

What is your favorite movie or TV show?
I have a few but considering the season, “Hocus Pocus!”

What do you like to do in your spare time?
Exploring the city, going to local festivals, getting creative, and trying new foods.

What is a fun fact about you?
I will turn almost anything into an art medium, if left unsupervised.