Researcher Spotlight: Scott Jenks

What is your professional background?
I have had an interest in science and biology since childhood and attended Ripon College, a small liberal arts college in Wisconsin. I received my PhD in immunology from the University of Chicago under the mentorship of Dr. Jim Miller, where I studied how costimulation influences T helper cell differentiation. I next performed post-doctoral research on immunodominance with Dr. Andrea Sant at the University of Rochester and then transitioned to human B cell immunology in my second post-doctoral position with Dr. Ignacio Sanz. I accompanied Dr. Sanz as a junior faculty member when he moved to Emory.

In what division do you work, and who is your mentor?
I am in the Division of Rheumatology and work in the Lowance Center for Human Immunology. I am fortunate to have Dr. Ignacio Sanz as a mentor; he has both extensive clinical experience in treating lupus and an incredible knowledge of human B cells.

Briefly describe your research. Why is it important?
Systemic Lupus varies widely in symptoms, severity, and prognosis. The first new lupus drug approved in over 50 years blocks a B cell survival factor and understanding B cell biology is key for better treatment. My research has examined the diversity of human B cells and defined an effector B cell population that is dramatically increased in many lupus patients. These B cells have an unusual developmental origin, are more prevalent in black patients, and are associated with lupus nephritis. We have subsequently established that there is great diversity in the types of B cells lupus patients have and want to use B cell phenotype to predict clinical outcomes and develop new treatment approaches.

What do you like most about Emory?
What I like most about Emory are my colleagues. It is a great environment to interact and collaborate with so many experienced and intelligent scientists. I also greatly appreciate my clinical colleagues at Emory. They value research and have helped me develop beyond my basic science background.

What do you like to do in your spare time?
In my spare time, I like to read science fiction and history. I also enjoy role playing and narrative games, and help run the monthly Atlanta Intown RPG Day.

What is your favorite movie or TV show?
Over the last few years, I have found most of my media viewing is YouTube videos, where I follow my curiosity in history, war gaming, and science.

What is a fun fact about you?
I share a birthday with Frederick Law Olmsted and for my entire adult life since college, I have lived within two miles of an Olmstead park.